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This is game-changing for women.” Unlike Viagra, which was approved by the FDA in 1998 and increases blood flow to the genitals, flibanserin targets neurotransmitters in the brain. Because the drug can cause sleepiness, Sprout recommends taking it before bed.Though just how the drug boosts desire remains unknown, flibanserin affects the levels of dopamine and norepinephrine in the brain, neurotransmitters that are key to sexual desire, and serotonin, which governs inhibition. Adriane Fugh-Berman, a pharmacology professor at Georgetown University and director of Pharmed Out, which focuses on pharmaceutical marketing practices, called Tuesday “a sad day for drug regulation.” “The FDA turned down this drug twice because the risks outweighed the benefits,” she said.
“It acknowledges that as a condition, HSDD is not simply a psychological problem or a reflection of cultural pressure on women but a biological condition that can be treated with an effective medication,” she said.“What has been learned since the last disapproval is that it has more risks than we thought and it doesn’t have any more benefits.The only thing that’s different is a clever, aggressive public relations campaign that Sprout Pharmaceuticals waged successfully.” She added: “This opens the way for drug companies to pressure the FDA through public relations campaigns to approve more bad drugs: It’s bad news for rational drug approval.” The FDA rejected the drug in 2010 and in 2013, saying the risks of side effects such as nausea, dizziness, low blood pressure, fainting and sleepiness outweighed the “modest” benefit.Normally, female chickens have just one functional ovary, on their left side.Although two sex organs are present during the embryonic stages of all birds, once a chicken's female genes kick in, it typically develops only the left ovary.